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(1S-cis)-Milnacipran Hydrochloride (CAS 175131-60-9) is a chemical compound that belongs to the class of drugs known as serotonin-norepinephrine reuptake inhibitors (SNRIs). It is the hydrochloride salt form of milnacipran.
Milnacipran is primarily used as an antidepressant medication and is indicated for the treatment of major depressive disorder (MDD) and fibromyalgia. The (1S-cis) enantiomer refers to the specific stereochemistry of the molecule.
The compound works by inhibiting the reuptake of both serotonin and norepinephrine in the brain, thereby increasing their availability and enhancing neurotransmission. This mechanism of action is believed to contribute to its antidepressant and analgesic effects.
|Appearance :||White or of- white powder or crystlline power,odorless|
|Physical State :||Solid|
|Solubility :||Very soluble in N,N-Dimethylformamide,Soluble in methanol,Sparingly soluble inglacial acetic acid, Very slightly soluble inchloroform, Practically insoluble in water.|
|Molecular Formula :||C15H23ClN2O|
|Melting Point :||105°C~115°C|
|Structural Features||Milnacipran is primarily used as an antidepressant medication and is indicated for the treatment of major depressive disorder (MDD) and fibromyalgia. The (1S-cis) enantiomer refers to the specific stereochemistry of the molecule.|
Some key features and applications of (1S-cis)-Milnacipran Hydrochloride include:
- Antidepressant: It is used to manage symptoms of depression, including low mood, loss of interest, and feelings of worthlessness or guilt.
- Fibromyalgia Treatment: Milnacipran is also approved for the treatment of fibromyalgia, a chronic pain condition characterized by widespread musculoskeletal pain, fatigue, and tenderness.
- Serotonin-Norepinephrine Reuptake Inhibitor (SNRI): As an SNRI, it selectively targets the reuptake of serotonin and norepinephrine, which may provide additional benefits compared to medications targeting only one neurotransmitter.
- Dosage and Administration: The appropriate dosage and administration regimen of (1S-cis)-Milnacipran Hydrochloride should be determined by a healthcare professional based on individual patient factors and needs.
It’s important to note that (1S-cis)-Milnacipran Hydrochloride should only be used under the guidance and supervision of a qualified healthcare provider. Adherence to prescribed dosages and regular monitoring is crucial for safety and efficacy.
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